Saturday, 22 February 2025

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2 weeks ago
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ABSTRACT BACKGROUND: Age is a major risk factor for venous thromboembolism (VTE), yet patients aged ≥90 years are under-represented in clinical trials of anticoagulant therapy. The objectives were to describe and compare patient clinical characteristics, treatments, and outcomes (VTE recurrence, bleeding, and mortality) during the first 3 months of anticoagulation between VTE patients aged ≥90 years and those aged <90 METHODS: We analyzed data from the Registro Informatizado Enfermedad TromboEmbὀlica (RIETE), an ongoing global observational registry of patients with objecti... más información
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ABSTRACT BACKGROUND: Incidence of and risk factors for bleeding in cancer patients with venous thromboembolism (VTE) treated with apixaban are poorly described. METHODS: We analyzed data from the prospective CAP study where 298 cancer patients with any type of VTE received 5 mg apixaban twice daily for 6 months, and then 2.5 mg apixaban twice daily for 30 months. For most analyses major bleedings and clinically relevant non-major bleedings were merged to "clinically relevant bleedings". Risk factors were estimated by odds ratios (OR) and 95% confidence intervals (CI). RES... más información
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ABSTRACT Venous thromboembolism (VTE) is a common complication in patients with cancer. Data on the role of natural inhibitors of coagulation for occurrence of cancerassociated VTE are limited, thus, we investigated the association of tissue factor pathway inhibitor (TFPI) with risk of VTE and all-cause mortality in patients with cancer. Total TFPI antigen levels were measured with a commercially available ELISA in patients included in the Vienna Cancer and Thrombosis Study, a prospective observational cohort study with the primary outcome VTE. Competing risk analysis and Cox... más información
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ABSTRACT The present review summarizes the beneficial and detrimental roles of reactive oxygen species in myocardial ischemia/reperfusion injury and cardioprotection. In the first part, the continued need for cardioprotection beyond that by rapid reperfusion of acute myocardial infarction is emphasized. Then, pathomechanisms of myocardial ischemia/reperfusion to the myocardium and the coronary circulation and the different modes of cell death in myocardial infarction are characterized. Different mechanical and pharmacological interventions to protect the ischemic/reperfused ... más información
welcom2 weeks ago
torneira automática
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welcom2 weeks ago
robinet automatique
robinet automatique robinet automatique - Maison - Conditions générales Traduction FrançaisAbkhazeAcehAcholiAfarAfrikaansAlbanaisAllemandAlurAmhariqueAnglais ArabeArménienAssamaisAvarAwadhiAymaraAzériBachkirBalinaisBaloutchiBambara BaouléBasqueBatak KaroBatak SimalungunBatak TobaBembaBengaliBetawiBhodjpouri BicolBiélorusseBirmanBosniaqueBouriateBretonBulgareCantonaisCatalanCebuano ChamorroChichewaChinois (simplifié)Chinois (traditionnel)ChuukCinghalais CoréenCorseCréole haïtienCréole mauricienCréole seychelloisCroateDanoisDari DinkaDioulaDivéhiDogriDombeDzongkhaEspagnolEspéran... más información

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