med 5

3 months ago

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Triethanolamine Nonproprietary Names BP: Triethanolamine PhEur: Trolaminum USPNF: Trolamine Synonyms TEA; Tealan; triethylolamine; trihydroxytriethylamine; tris (hydroxyethyl)amine. Chemical Names and CAS Registry Number 2,2',2''-Nitrilotriethanol [102-71-6] Empirical Formula and Molecular Weight C6H15NO3 149.19 Structural Formula Functional Category Alkalizing agent; emulsifying agent. Applications in Pharmaceutical Formulation or Technology Triethanolamine is widely used in topical pharmaceutical formulations primarily in the formation of emulsions. When m... más información

med 53 months ago

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Related Substances Menthol. Comments The EINECS number for thymol is 201-944-8. Specific References Didry N, Dubreuil L, Pinkas M. Activity of thymol, carvacrol, cinnamaldehyde and eugenol on oral bacteria. Pharm Acta Helv 1994; 69(1): 25–28. Didry N, Dubreuil L, Pinkas M. Antimicrobial activity of thymol, carvacrol and cinnamaldehyde alone or in combination. Pharma- zie 1993; 48: 301–304. Gao S, Singh J. Mechanism of transdermal transport of 5- fluorouracil by terpenes: carvone, 1,8-cineole and thymol. Int J Pharm 1997; 154(1): 67–77. Doliwa A, Santoyo S, Ygartua P. Effe... más información

med 53 months ago

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Pharmacopeial Specifications See Table I. Table I: Pharmacopeial specifications for tartaric acid. Test JP 2001 PhEur 2005 USPNF 23 Identification + + + Characters — + — Appearance of solution — + — Specific rotation — +12.08 to +12.08 to +12.88 +13.08 Loss on drying 40.5% 40.2% 40.5% Sulfated ash — 40.1% — Residue on ignition 40.05% — 40.1% Organic volatile — — + impurities Chloride — 4100 ppm — Oxalic acid — 4350 ppm — Oxalate + — + Sulfate 40.048% 4150 ppm + Calcium + 4200 ppm — Heavy metals 410 ppm 410 ppm 40.... más información

med 53 months ago

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Applications in Pharmaceutical Formulation or Technology Sulfuric acid is used as an acidifying agent in a variety of pharmaceutical and food preparations. It may also be used to prepare dilute sulfuric acid, which, in addition to its use as an excipient, has some therapeutic use for the treatment of gastric hypoacidity, as an astringent in diarrhea, or to stimulate appetite. Sulfuric acid has been used in parenteral, oral, topical, and ophthalmic pharmaceutical formulations. Description Sulfuric acid occurs as a clear, colorless, odorless, oily liquid. It is very corrosiv... más información

med 53 months ago

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For this reason, its use in oral pharmaceutical formulations is declining. Although sucrose has been associated with obesity, renal damage, and a number of other diseases, conclusive evidence linking sucrose intake with some diseases could not be established.(12,13) It was, however, recommended that sucrose intake in the diet should be reduced.(13) LD50 (mouse, IP): 14 g/kg(14) LD50 (rat, oral): 29.7 g/kg Handling Precautions Observe normal precautions appropriate to the circumstances and quantity of material handled. Eye protection and gloves are recommended. In the UK, the oc... más información

med 53 months ago

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Handling Precautions Observe normal precautions appropriate to the circumstances and quantity of material handled. Stearic acid dust may be irritant to the skin, eyes, and mucous membranes. Eye protection, gloves, and a dust respirator are recommended. Stearic acid is combustible. Stearic Acid 739 Table III: Specifications of different stearic acid grades. Regulatory Status GRAS listed. Accepted as a food additive in Europe (fatty acids). Included in the FDA Inactive Ingredients Guide (sublingual tablets; oral capsules, solutions, suspensions, and tablets; topical... más información

med 53 months ago

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SEM: 4 Excipient: Rice starch Supplier: Matheson, Coleman & Bell Magnification: 600× 728 Starch SEM: 5 Excipient: Rice starch Supplier: Matheson, Coleman & Bell Magnification: 3000× SEM: 6 Excipient: Wheat starch (Paygel 55) Manufacturer: Henkel Corp. Lot No.: 96A-1 (2917D) Magnification: 2400× Voltage: 20 kV SEM: 7 Excipient: Wheat starch (Aytex P) Manufacturer: Henkel Corp. Lot No.: 96A-2 (2919D) Magnification: 2400× Voltage: 20 kV Stability and Storage Conditions Dry, unheated starch is stable if protected from high humidity. ... más información