3 months ago
UntitledComments Xanthan gum is available in several different grades that have varying particle sizes. Fine-mesh grades of xanthan gum are used in applications where high solubility is desirable since they dissolve rapidly in water. However, fine-mesh grades disperse more slowly than coarse grades and are best used dry blended with the other ingredients of a formulation. In general, it is preferable to dissolve xanthan gum in water first and then add the other ingredients of a formulation. When added to liquid ophthalmics, xanthan gum delays the release of active substances, increas... más información
med 53 months ago
UntitledWax, White Nonproprietary Names BP: White beeswax JP: White beeswax PhEur: Cera alba USPNF: White wax Synonyms Bleached wax; E901. Chemical Name and CAS Registry Number White beeswax [8012-89-3] Empirical Formula and Molecular Weight White wax is the chemically bleached form of natural beeswax; see Section 13. Beeswax consists of 70–75% of a mixture of various esters of straight-chain monohydric alcohols with even-numbered carbon chains from C24 to C36 esterified with straight-chain acids. These straight-chain acids also have even numbers of carbon atoms up to C36 tog... más información
med 53 months ago
UntitledComments In cosmetics, carnauba wax is mainly used to increase the stiffness of formulations, e.g. lipsticks and mascaras. The EINECS number for carnauba wax is 232-399-4. Specific References Ema˚ s M, Nyqvist H. Methods of studying aging and stabilization of spray-congealed solid dispersions with carnauba wax. 1: microcalorimetric investigation. Int J Pharm 2000; 197: 117–127. Marti-Mestres G, Nielland F, Rigal S, et al. Texture and sensory analysis in stick formulations. STP Pharma Sci 1999; 9(4): 371– 375. Reza MS, Quadir MA, Haider SS. Comparative evaluation of plastic, h... más información
med 53 months ago
UntitledStability and Storage Conditions Water is chemically stable in all physical states (ice, liquid, and vapor). Water for specific purposes should be stored in appropriate containers; see Table III. Table II: Pharmacopeial specifications of water for different pharmaceutical applications. Test Water JP 2001 Purified water JP 2001 Purified water in bulk Purified water in containers Purified Water, water highly USP 28 purified Sterile water for injection Bacteriostatic water for injection Sterile water for inhalation Sterile water for irrigation Sterile Water for puri... más información
med 53 months ago
UntitledSynonyms Aqua; hydrogen oxide. Potable water Public supply suitable for drinking, the purity of which is unlikely to be suitable for use in the manufacture of pharmaceuticals. Purified water Vehicle and solvent for the manufacture of drug products and pharmaceutical preparations; not suitable for use in the manufacture of parenteral products. Chemical Name and CAS Registry Number Water [7732-18-5] Empirical Formula and Molecular Weight H2O 18.02 Sterile water for inhalation Sterile water for injection Sterile water for irrigation Water for injections in bulk Diluent fo... más información
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